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29-Jul-2014 | 582-EN

Implants based on alginate for use in wound care

Christine Lämmle receives research prize from DGfW

BÖNNIGHEIM (ri) Christine Lämmle has won this year's research prize from the German Society for Wound Healing (DGfW). At the DGfW's 17th annual conference in Bochum, she was presented with the prize for "establishing an alginate implant colonised with stem cells for use in autologous soft tissue replacement".

Mrs Lämmle worked as part of her doctorate on this partnership project run by the Department for Hygiene, Environment and Medicine at the Hohenstein Institute (Prof. Dr. D. Höfer) and the AG Experimentelle Plastische Chirurgie at the Bergmannsheil BG University Clinic, Bochum (led by PD Dr. T. Hirsch, Dr. F. Jacobsen).

It is hoped that their success in converting the body's own stem cells into adipocytes (fat cells) and colonising them on 3D implants will help in the treatment of damaged soft tissue in future. Filling large injuries such as burns, pressure ulcers and large scars is a particular challenge in reconstructive surgery. Most surgeons currently choose flap surgery for tissue reconstruction. This technique puts great strain on the surrounding healthy tissue and therefore on the entire patient.

The alginate implants represent a very promising alternative. Their development was based both on earlier research work carried out at the Hohenstein Institute on combining biopolymers and stem cells in soft tissue replacement, and on the expertise of the Bergmannsheil working group on wound healing and tissue replacement.

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